منابع مشابه
Modification of infarct size.
To the Editor: The article by Maroko and his co-workers entitled "Factors Influencing Infarct Size Following Experimental Coronary Artery Occlusions" (Circulation 43:67, 1971) is indeed a very interesting one and an enthusiastic approach to the problem of modification of the size of an infarct. However, there are several points with regard to the methods that seem to need some clarification. Th...
متن کاملThe quantification of infarct size.
We sought to summarize the published evidence regarding the measurement of infarct size by serum markers, technetium-99m sestamibi single-photon emission computed tomography (SPECT) myocardial perfusion imaging, and magnetic resonance imaging. The measurement of infarct size is an attractive surrogate end point for the early assessment of new therapies for acute myocardial infarction. For each ...
متن کاملSelective inhibition of the contractile apparatus. A new approach to modification of infarct size, infarct composition, and infarct geometry during coronary artery occlusion and reperfusion.
BACKGROUND Myocardial reperfusion is associated with calcium overload and cell contracture, mechanisms that may precipitate cell death. In this study, we tested the hypothesis that in vivo inhibition of this contracture could lead to cell preservation in an open-chest large animal model. METHODS AND RESULTS Regional myocardium function was measured during a selective intracoronary infusion of...
متن کاملRelationship Between Myocardial Infarct Size
We compared myocardial infarct size produced by permanent occlusion of the middle left anterior descending (LAD) or circumflex (LCx) coronary artery in the anesthetized dog. The dogs were killed 3-10 days later, and the occluded coronary bed was visualized by postmortem arteriography. The outlines of the infarct and occluded bed were marked on tracings of weighed left ventricular (LV) rings and...
متن کاملEvaluation of Vapor Deposition Techniques for Membrane Pore Size Modification
The suitability of three vapor deposition techniques for pore size modification was evaluated using polycarbonate track etched membranes as model supports. A feature scale model was employed to predict the pore geometry after modification and the resulting pure water flux. Physical vapor deposition (PVD) and pulsed plasma-enhanced chemical vapor deposition (PECVD), naturally, form asymmetric na...
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ژورنال
عنوان ژورنال: Circulation
سال: 1971
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.43.2.317